Article 16418

Title of the article

CAUSES OF DEATH AMONG HIV-INFECTED PATIENTS IN THE PENZA REGION 

Authors

Mel'nikov Viktor L'vovich, Doctor of medical sciences, head of the sub-department of microbiology, epidemiology and infectious diseases, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), E-mail: meidpgumi@yandex.ru
Kurmaeva Dzhamilya Yusupovna, Candidate of medical sciences, associate professor, sub-department of microbiology, epidemiology and infectious diseases, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia); deputy chief of the medical officer, Penza Regional Clinical Center for Specialized Types of Medical Care (23 Krasnaya street, Penza, Russia), E-mail: meidpgumi@yandex.ru
Nikol'skaya Marina Viktorovna, Candidate of medical sciences, associate professor, sub-department of microbiology, epidemiology and infectious diseases, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), E-mail: missmarina1956@yandex.ru
Rybalkin Sergey Borisovich, Candidate of medical sciences, associate professor, sub-department of microbiology, epidemiology and infectious diseases, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia); head of the medical officer, Penza Regional Clinical Center for Specialized Types of Medical Care (23 Krasnaya street, Penza, Russia), E-mail: meidpgumi@yandex.ru
Nikulina Yuliya Aleksandrovna, Student, Medical institute, Penza State University (40 Krasnaya street, Penza, Russia), E-mail: nikulina1995@mail.ru 

Index UDK

616.98:578.828 

DOI

10.21685/2072-3032-2018-4-16 

Abstract

Background. The causes and structure of deaths in HIV-infected patients in the Penza region for the period 2014–2017 were studied.
Materials and methods. A retrospective study of the medical histories and protocols of post mortem studies 338 deceased patients with laboratory-confirmed HIV infection. The study analyzed gender factors, experience of HIV infection before death, the stage of the disease at the dispensary and at the time of death, laboratory indicators, as well as the main causes of deaths.
Results. Between 2014 and 2017, 338 HIV – infected people were reported to have died; in 46,2 % of cases, the cause of death was the progression of HIV infection. Among the deceased patients, non – working men prevailed – 182 (53,8 %), residents of the cities of the region. In most patients, HIV infection was diagnosed at the age of 20 to 35 years – 226 (66,8 %) people. Deaths occurred more often at the age of 31 to 40 years – 60,3 %, in the stage of secondary diseases– 75,1 % of patients. Among the causes of death from HIV infection, tuberculosis occupies the leading place-58,9 % and CNS damage – 14,1 % of the dead.
Conclusions. In the structure of deaths in patients with HIV infection, opportunistic diseases accounted for 46,2 % of cases. Low adherence to therapy was revealed in the dead patients. At the time of death, the stage of secondary diseases was observed in 254 (75,1 %) patients. Among the opportunistic diseases the leading place was occupied by mycobacterial infection – 92 (58,9 %) patients. 

Key words

HIV infection, causes of death, opportunistic infections 

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Дата создания: 17.06.2019 13:40
Дата обновления: 18.06.2019 08:20